Z79.621 Long term (current) use of calcineurin inhibitor
ICD-10-CM · CMS code reference
Official ICD-10-CM description: Long term (current) use of calcineurin inhibitor
Coding notes
From the ICD-10-CM FY2027 (effective October 1, 2026) tabular list. Notes on a parent code or category apply here too.
Also covers
- Long term (current) use of cyclosporine
- Long term (current) use of tacrolimus
Includes
- long term (current) drug use for prophylactic purposes
Excludes2
Not part of this code, but both can be coded when both are documented.
- long term (current) use of steroids (Z79.5-)
- long term (current) use of agents affecting estrogen receptors and estrogen levels (Z79.81-)
- drug abuse and dependence (F11-F19)
- drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)
Code also
A second code may be needed. Sequencing depends on the encounter.
Related codes
Z79.60Long term (current) use of unspecified immunomodulators and immunosuppressants ICD-10-CMZ79.61Long term (current) use of immunomodulator ICD-10-CMZ79.620Long term (current) use of immunosuppressive biologic ICD-10-CMZ79.622Long term (current) use of Janus kinase inhibitor ICD-10-CMZ79.623Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor ICD-10-CMZ79.624Long term (current) use of inhibitors of nucleotide synthesis ICD-10-CMZ79.630Long term (current) use of alkylating agent ICD-10-CMZ79.631Long term (current) use of antimetabolite agent ICD-10-CM
Common questions
Is Z79.621 a billable code?
Yes. Z79.621 is a billable ICD-10-CM code in the ICD-10-CM FY2027 (effective October 1, 2026) code set.