---
title: "ICD-10-CM Z79.61: Long term (current) use of immunomodulator | BillingBrief"
description: "ICD-10-CM code Z79.61: Long term (current) use of immunomodulator. Category, related codes, and the official source, in plain English."
canonical: "https://billingbrief.com/icd10/z79.61/"
language: "en"
---

# Z79.61 Long term (current) use of immunomodulator

ICD-10-CM · [CMS code reference](#source)

**Official ICD-10-CM description:** Long term (current) use of immunomodulator

## Coding notes

From the ICD-10-CM FY2027 (effective October 1, 2026) tabular list. Notes on a parent code or category apply here too.

### Also covers

-   Long term (current) use of apremilast
-   Long term (current) use of immunomodulatory imide drug
-   Long term (current) use of lenalidomide
-   Long term (current) use of pomalidomide

### Includes

-   long term (current) drug use for prophylactic purposes

### Excludes2

Not part of this code, but both can be coded when both are documented.

-   long term (current) use of steroids (Z79.5-)
-   long term (current) use of agents affecting estrogen receptors and estrogen levels (Z79.81-)
-   drug abuse and dependence (F11-F19)
-   drug use complicating pregnancy, childbirth, and the puerperium (O99.32-)

### Code also

A second code may be needed. Sequencing depends on the encounter.

-   any therapeutic drug level monitoring ([Z51.81](https://billingbrief.com/icd10/z51.81/))
-   any follow-up examination (Z08-[Z09](https://billingbrief.com/icd10/z09/))

## Related codes

-   [`Z79.60` Long term (current) use of unspecified immunomodulators and immunosuppressants ICD-10-CM](https://billingbrief.com/icd10/z79.60/)
-   [`Z79.620` Long term (current) use of immunosuppressive biologic ICD-10-CM](https://billingbrief.com/icd10/z79.620/)
-   [`Z79.621` Long term (current) use of calcineurin inhibitor ICD-10-CM](https://billingbrief.com/icd10/z79.621/)
-   [`Z79.622` Long term (current) use of Janus kinase inhibitor ICD-10-CM](https://billingbrief.com/icd10/z79.622/)
-   [`Z79.623` Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor ICD-10-CM](https://billingbrief.com/icd10/z79.623/)
-   [`Z79.624` Long term (current) use of inhibitors of nucleotide synthesis ICD-10-CM](https://billingbrief.com/icd10/z79.624/)
-   [`Z79.630` Long term (current) use of alkylating agent ICD-10-CM](https://billingbrief.com/icd10/z79.630/)
-   [`Z79.631` Long term (current) use of antimetabolite agent ICD-10-CM](https://billingbrief.com/icd10/z79.631/)

## Common questions

### Is Z79.61 a billable code?

Yes. Z79.61 is a billable ICD-10-CM code in the ICD-10-CM FY2027 (effective October 1, 2026) code set.

## From the source

Official description from [CMS](https://www.cms.gov/medicare/coding-billing/icd-10-codes).
ICD-10-CM FY2027 (effective October 1, 2026).

Code set

ICD-10-CM

Category

Z79 Long term (current) drug therapy

Chapter

Factors influencing health status and contact with health services

Billable

Yes

Educational reference only. Not medical, legal, or billing advice. Always check the current official code set and payer policy before you bill. [About BillingBrief and our sources](https://billingbrief.com/about/).