---
title: "ICD-10-CM R53.0: Neoplastic (malignant) related fatigue | BillingBrief"
description: "ICD-10-CM code R53.0: Neoplastic (malignant) related fatigue. Category, related codes, and the official source, in plain English."
canonical: "https://billingbrief.com/icd10/r53.0/"
language: "en"
---

# R53.0 Neoplastic (malignant) related fatigue

ICD-10-CM · [CMS code reference](#source)

**Official ICD-10-CM description:** Neoplastic (malignant) related fatigue

## Coding notes

From the ICD-10-CM FY2027 (effective October 1, 2026) tabular list. Notes on a parent code or category apply here too.

### Code first

Code the underlying condition first, then this code.

-   associated neoplasm

## Related codes

-   [`R53.1` Weakness ICD-10-CM](https://billingbrief.com/icd10/r53.1/)
-   [`R53.2` Functional quadriplegia ICD-10-CM](https://billingbrief.com/icd10/r53.2/)
-   [`R53.81` Other malaise ICD-10-CM](https://billingbrief.com/icd10/r53.81/)
-   [`R53.82` Chronic fatigue, unspecified ICD-10-CM](https://billingbrief.com/icd10/r53.82/)
-   [`R53.83` Other fatigue ICD-10-CM](https://billingbrief.com/icd10/r53.83/)

## Common questions

### Is R53.0 a billable code?

Yes. R53.0 is a billable ICD-10-CM code in the ICD-10-CM FY2027 (effective October 1, 2026) code set.

## From the source

Official description from [CMS](https://www.cms.gov/medicare/coding-billing/icd-10-codes).
ICD-10-CM FY2027 (effective October 1, 2026).

Code set

ICD-10-CM

Category

R53 Malaise and fatigue

Chapter

Symptoms, signs and abnormal clinical and laboratory findings

Billable

Yes

Educational reference only. Not medical, legal, or billing advice. Always check the current official code set and payer policy before you bill. [About BillingBrief and our sources](https://billingbrief.com/about/).