---
title: "ICD-10-CM F11.281: Opioid dependence with opioid-induced… | BillingBrief"
description: "F11.281 is for opioid dependence with sexual dysfunction documented as opioid-induced (caused by opioids). With opioid abuse, the matching code is F11.181…"
canonical: "https://billingbrief.com/icd10/f11.281/"
language: "en"
---

# F11.281 Opioid dependence with opioid-induced sexual dysfunction

ICD-10-CM · [CMS code reference](#source)

F11.281 is for opioid dependence with sexual dysfunction documented as opioid-induced (caused by opioids). With opioid abuse, the matching code is F11.181; with use not described as abuse or dependence, F11.981.

## Coding notes

From the ICD-10-CM FY2027 (effective October 1, 2026) tabular list. Notes on a parent code or category apply here too.

### Excludes1

Not coded together with this code. The exception is when the two conditions are unrelated to each other.

-   opioid abuse (F11.1-)
-   opioid use, unspecified (F11.9-)

### Excludes2

Not part of this code, but both can be coded when both are documented.

-   opioid poisoning (T40.0-T40.2-)

## Related codes

-   [`F11.23` Opioid dependence with withdrawal ICD-10-CM](https://billingbrief.com/icd10/f11.23/)
-   [`F11.24` Opioid dependence with opioid-induced mood disorder ICD-10-CM](https://billingbrief.com/icd10/f11.24/)
-   [`F11.250` Opioid dependence with opioid-induced psychotic disorder with delusions ICD-10-CM](https://billingbrief.com/icd10/f11.250/)
-   [`F11.251` Opioid dependence with opioid-induced psychotic disorder with hallucinations ICD-10-CM](https://billingbrief.com/icd10/f11.251/)
-   [`F11.259` Opioid dependence with opioid-induced psychotic disorder, unspecified ICD-10-CM](https://billingbrief.com/icd10/f11.259/)
-   [`F11.282` Opioid dependence with opioid-induced sleep disorder ICD-10-CM](https://billingbrief.com/icd10/f11.282/)
-   [`F11.288` Opioid dependence with other opioid-induced disorder ICD-10-CM](https://billingbrief.com/icd10/f11.288/)
-   [`F11.29` Opioid dependence with unspecified opioid-induced disorder ICD-10-CM](https://billingbrief.com/icd10/f11.29/)

## Common questions

### Is F11.281 a billable code?

Yes. F11.281 is a billable ICD-10-CM code in the ICD-10-CM FY2027 (effective October 1, 2026) code set.

## From the source

Official description from [CMS](https://www.cms.gov/medicare/coding-billing/icd-10-codes).
ICD-10-CM FY2027 (effective October 1, 2026).

Code set

ICD-10-CM

Category

F11 Opioid related disorders

Chapter

Mental, behavioral and neurodevelopmental disorders

Billable

Yes

Educational reference only. Not medical, legal, or billing advice. Always check the current official code set and payer policy before you bill. [About BillingBrief and our sources](https://billingbrief.com/about/).