---
title: "ICD-10-CM E53.1: Pyridoxine deficiency | BillingBrief"
description: "ICD-10-CM code E53.1: Pyridoxine deficiency. Category, related codes, and the official source, in plain English."
canonical: "https://billingbrief.com/icd10/e53.1/"
language: "en"
---

# E53.1 Pyridoxine deficiency

ICD-10-CM · [CMS code reference](#source)

**Official ICD-10-CM description:** Pyridoxine deficiency

## Coding notes

From the ICD-10-CM FY2027 (effective October 1, 2026) tabular list. Notes on a parent code or category apply here too.

### Also covers

-   Vitamin B6 deficiency

### Excludes1

Not coded together with this code. The exception is when the two conditions are unrelated to each other.

-   pyridoxine-responsive sideroblastic anemia ([D64.3](https://billingbrief.com/icd10/d64.3/))
-   sequelae of vitamin B deficiency (E64.8)

### Excludes2

Not part of this code, but both can be coded when both are documented.

-   nutritional anemias (D50-D53)

## Related codes

-   [`E53.0` Riboflavin deficiency ICD-10-CM](https://billingbrief.com/icd10/e53.0/)
-   [`E53.8` Deficiency of other specified B group vitamins ICD-10-CM](https://billingbrief.com/icd10/e53.8/)
-   [`E53.9` Vitamin B deficiency, unspecified ICD-10-CM](https://billingbrief.com/icd10/e53.9/)

## Common questions

### Is E53.1 a billable code?

Yes. E53.1 is a billable ICD-10-CM code in the ICD-10-CM FY2027 (effective October 1, 2026) code set.

## From the source

Official description from [CMS](https://www.cms.gov/medicare/coding-billing/icd-10-codes).
ICD-10-CM FY2027 (effective October 1, 2026).

Code set

ICD-10-CM

Category

E53 Deficiency of other B group vitamins

Chapter

Endocrine, nutritional and metabolic diseases

Billable

Yes

Educational reference only. Not medical, legal, or billing advice. Always check the current official code set and payer policy before you bill. [About BillingBrief and our sources](https://billingbrief.com/about/).